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Your PRODIGY prediction (ExampleProdigy) has finished successfully.

Please note that the results will be deleted after two weeks.

To cite PRODIGY, please refer to:

  1. Vangone A. and Bonvin A.M.J.J. "Contact-based prediction of binding affinity in protein-protein complexes", eLife, 4, e07454 (2015).
  2. Xue L., Rodrigues J., Kastritis P., Bonvin A.M.J.J.*, Vangone A.*, "PRODIGY: a web-server for predicting the binding affinity in protein-protein complexes", Bioinformatics, doi:10.1093/bioinformatics/btw514 (2016).

For more information about the predictive model please check the PRODIGY prediction method page.

Further information can be found in the PRODIGY Manual and an example of the PRODIGY output can be found here.

Back to PRODIGY home page

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Binding affinity and Kd prediction

Protein-protein complex ΔG (kcal mol-1) Kd (M) at ℃ ICs charged-charged ICs charged-polar ICs charged-apolar ICs polar-polar ICs polar-apolar ICs apolar-apolar NIS charged NIS apolar
1e6j -9.1 2.1e-07 0 7 8 5 15 26 20.48 38.77

Download outputs

Archive file of all the outputs (.zip)
- Residue-residue pairs (.ic)
- PyMol ICs-based representation script (.pml)
- PDB file (.pdb)
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This work is co-funded by the Horizon 2020 projects EOSC-hub and EGI-ACE (grant numbers 777536 and 101017567), BioExcel (grant numbers 823830 and 675728)
and by a computing grant from NWO-ENW (project number 2019.053).